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In the scientific literature, it is described as a triple agonist of the GLP-1, GIP and glucagon receptors (GCGR)
1.4 Objective of this review This review collates the recent literature on the evolving evidence supporting the discourse on the recognition of PDM as a new clinical condition
Its unique mechanism targets GLP-1 alongside glucagon receptor pathways, and studies examine its metabolic effects on energy expenditure, energy balance, glucose regulation, and gastric emptying
At the primary endpoint, participants receiving retatrutide achieved substantial reductions in body weight from a mean baseline weight of 234.6 lbs
Some patients report receiving medication within a week
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